TCOM Viewer TCOM Viewer is a software interface between Windows PCs and Orenco’s TCOM remote telemetry control panels. The interface stores configurations for multiple sites, has a simplified “double-click to select” mouse interface for menu items, and offers new screen color choices for better visibility. Sites can be sorted by factory identification number or by operator-designated panel name. The interface helps facility managers and operators take full advantage of TCOM’s SCADA functionality, such as remote access and control, plus the ability to retrieve and graph log data from monitored panels. The basic viewer is available to TCOM customers at no charge and works with virtually all TCOM panels, no matter when they were installed. Some customers might choose to upgrade to a TCOM viewer graphical interface; this interface is a less-expensive alternative to a panel-mounted touchscreen, especially for installations that are visited only occasionally. Our controls engineers can help determine whether your site’s panel can be configured with the graphical interface.

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Methods Outflow facility ( C) and pressure-independent outflow ( F u) were assessed by multilevel constant pressure perfusion of enucleated eyes from C57BL/6 mice. To examine the effect of hydration, seven eyes were perfused at room temperature, either immersed to the limbus in saline and covered with wet tissue paper or exposed to room air. Download groove theory groove theory zip sweater. Temperature effects were examined in 12 eyes immersed in saline at 20°C or 35°C. Anterior chamber deepening was examined in 10 eyes with the cannula tip placed in the anterior versus posterior chamber (PC). Posterior bowing of the iris (AC deepening) was visualized by three-dimensional histology in perfusion-fixed C57BL/6 eyes and by spectral-domain optical coherence tomography in living CD1 mice. Mice are a common animal model for studies of aqueous humor dynamics and outflow physiology.

The anatomy of the conventional outflow pathway in mice is similar to that of humans with a continuous Schlemm's canal and lamellated trabecular meshwork. Like primates, mice possess a ciliary muscle that forms tendinous connections to the elastic fiber net of the trabecular meshwork and the inner wall endothelium of Schlemm's canal. Compounds that affect outflow facility in humans, including pilocarpine,, TGF-β2,, latanoprost – prostaglandin EP 4 receptor agonist, – and sphingosine 1-phosphate,, similarly affect outflow facility in mice. Recently, mice have been used to validate novel compounds that increase outflow facility based on hits from screening assays of cellular contractility. Numerous investigators have measured outflow facility in mice.,,,,,– However, on account of the small dimensions of the mouse eye and the low flow rates involved, there is greater potential for physical factors to influence ocular perfusion measurements in mice compared with larger species. For example, evaporation from the surface of the eye, which is more pronounced in smaller eyes that have a larger surface to volume ratio, may lead to dehydration of the corneoscleral shell and artifactually increase the apparent outflow rate. Importantly, this effect would manifest as a pressure-independent outflow during perfusion.

Posterior bowing of the iris, known as anterior chamber (AC) deepening, artificially increases outflow facility by applying traction to the trabecular meshwork., Anterior chamber deepening typically occurs during ocular perfusion via the AC, when the pressure in the AC exceeds that in the posterior chamber (PC). The pressure difference causes the iris–lens channel to collapse like a 1-way valve, preventing pressure equilibration across the iris. Anterior chamber deepening can be prevented by perfusion via the PC, by creating a fluidic shunt across the iris, or by iridectomy. Sega mega drive games list.